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Enterocyte Cytoskeleton: Its Structure and Function

Thomas C. S. Keller, Mark S. Mooseker

10.1002/cphy.cp060406

Source: Supplement 19: Handbook of Physiology, The Gastrointestinal System, Intestinal Absorption and Secretion

Originally published: 1991

Published online: January 2011

Full Article on Wiley Online Library



Abstract

The sections in this article are:

1 Brush‐Border Structure: Overview
1.1 Microvillus Core
1.2 Terminal Web
2 Components of Brush‐Border Cytoskeleton
2.1 Microvilli
2.2 Terminal Web
3 Functional Properties of Brush‐Border Cytoskeleton
3.1 Microvilli: Their Functional Properties
3.2 Terminal Web: Two Functional Domains?
4 Assembly of Brush‐Border Cytoskeleton
5 Functions of Other Cytoskeletal Components
5.1 Intermediate Filaments
5.2 Microtubules
6 Note Added in Proof
Figure 1. Figure 1.

Working model depicting organization and major proteins of brush‐border cytoskeleton. Model for the structure of cytoskeletal apparatus underlying brush‐border membrane summarizes work from numerous laboratories. Some components, e.g., 80‐kDa and 33‐kDa proteins in microvilli and caldesmon and p36 in terminal web, are shown as present but have yet to be designated as structural components. CM, calmodulin; ZA, zonula adherens; TM, tropomyosin.

[Adapted from Mooseker 89, 90.]


Figure 1.

Working model depicting organization and major proteins of brush‐border cytoskeleton. Model for the structure of cytoskeletal apparatus underlying brush‐border membrane summarizes work from numerous laboratories. Some components, e.g., 80‐kDa and 33‐kDa proteins in microvilli and caldesmon and p36 in terminal web, are shown as present but have yet to be designated as structural components. CM, calmodulin; ZA, zonula adherens; TM, tropomyosin.

[Adapted from Mooseker 89, 90.]
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Article Title: Enterocyte Cytoskeleton: Its Structure and Function
 

How to Cite

Thomas C. S. Keller, Mark S. Mooseker. Enterocyte Cytoskeleton: Its Structure and Function. Compr Physiol 2011, Supplement 19: Handbook of Physiology, The Gastrointestinal System, Intestinal Absorption and Secretion: 209-221. First published in print 1991. doi: 10.1002/cphy.cp060406