Preface
Edward J. Masoro
Pages: v-v

Aging: Current Concepts
Edward J. Masoro
Pages: 3-21

Design and Analysis of Aging Studies
Paul T. Costa, Robert R. McCrae
Pages: 25-36

Animal Models
Richard Weindruch
Pages: 37-52

Cell Culture as a Model
Vincent J. Cristofalo, Robert J. Pignolo
Pages: 53-82

Human Studies
Denis A. Evans
Pages: 83-92

Energy Utilization
Roger J. M. McCarter
Pages: 95-118

Carbohydrate Metabolism
Jeffrey B. Halter
Pages: 119-145

Aging, Fat Metabolism, and Adiposity
Dariush Elahi, Marianne McAloon Dyke, Reubin Andres, Anders Nilsson, Olle G. P. Isaksson
Pages: 147-170

Gene Expression and Protein Degradation
Holly Van Remmen, Walter F. Ward, Robert V. Sabia, Arlan Richardson
Pages: 171-234

Aging of Long-Lived Proteins: Extracellular Matrix (Collagens, Elastins, Proteoglycans) and Lens Crystallins
David R. Sell, Vincent M. Monnier
Pages: 235-305

Skin
Anjali Chuttani, Barbara A. Gilchrest
Pages: 309-324

Human Nervous System
Robert Katzman
Pages: 325-344

Maintenance and Regulation in Brain of Neurotransmission, Trophic Factors, and Immune Responses
Carl W. Cotman, Jennifer S. Kahle, Andrew R. Korotzer
Pages: 345-362

Taste and Smell
Linda Bartoshuk, Valerie Duffy
Pages: 363-375

The Potential Role of Selected Endocrine Systems in Aging Processes
James F. Nelson
Pages: 377-394

Bone
Dike N. Kalu
Pages: 395-412

Cardiovascular System
Edward G. Lakatta
Pages: 413-474

Respiratory System
David Sparrow, Scott T. Weiss
Pages: 475-483

Renal and Urinary Tract Function
Robert D. Lindeman
Pages: 485-503

The Gastrointestinal Tract
Peter R. Holt
Pages: 505-554

Immune System
Richard A. Miller
Pages: 555-590

Loss of Integration and Resiliency with Age: A Dissipative Destruction
F. Eugene Yates, Laurel A. Benton
Pages: 591-610

Putative Interventions
Byung P. Yu
Pages: 613-631

Exercise
John O. Holloszy, Wendy M. Kohrt
Pages: 633-666